Skip to content
Jump To:
Selected Item

Key Points/Overview

Phthalic anhydride is a white, crystalline chemical primarily used in industrial settings to manufacture plasticizers, resins, and dyes. It plays a critical role in producing flexible plastics (like PVC), durable coatings, and pigments for consumer and commercial products.

Phthalic anhydride is not typically present in finished consumer goods; instead, it is converted into plasticizers, resins, and dyes during manufacturing.

In occupational environments, direct exposure to its dust or vapors may cause irritation or sensitization, but these risks are well-managed with proper safety protocols such as ventilation and protective equipment. OSHA sets workplace exposure limits, ACGIH provides additional threshold limit values (TLVs) as safety guidelines, and the EPA regulates environmental releases.

Uses & Benefits

Phthalic anhydride is a key raw material in chemical manufacturing. Its most common uses include:

Front Seats Modern Car

Automotive

Phthalic anhydride is an ingredient in PVC components for interiors, alkyd coatings for finishes, and fiberglass resins for body panels.

PVC Pipes

Building & Construction

Phthalic anhydride-derived plasticizers add flexibility to PVC pipes, flooring, and wall coverings; alkyd resins provide durable paints and varnishes; fiberglass resins strengthen panels and insulation.

ethernet cables in a variety of colors

Consumer Goods

Phthalic anhydride-based coating enhances durability of appliances and furniture; PA-derived plasticizers are used in PVC wiring and cables.

Colored pigments

Textiles, Dyes & Pigments

Phthalic anhydride is an intermediate for dyes, pigments, inks, and textile finishes.

Manufacturers Engineer and tablet working at plastic bag manufacturers.

Safety Information

Phthalic anhydride is handled mainly in industrial settings. Workplace safety measures such as enclosed systems, ventilation, goggles, and gloves minimize exposure. Short-term exposure can cause irritation, and some workers may develop sensitivity with prolonged contact. OSHA and ACGIH establish workplace exposure limits, while the EPA regulates environmental releases. Unlike OSHA, ACGIH is not a regulatory agency, and its recommended exposure limits are advisory rather than legally enforceable.

Phthalic Anhydride Exposure

Phthalic anhydride is primarily handled in industrial settings, where protective measures, such as ventilation systems, enclosed processes, and personal protective equipment, are in place to reduce exposure.

  • Inhalation: May cause respiratory irritation. Prolonged exposure to vapors or dust may lead to sensitization in some workers.
  • Skin and Eye Contact: Can cause irritation on contact. Safety goggles and gloves are recommended in occupational settings.
  • Regulation: OSHA sets enforceable exposure limits, while ACGIH provides advisory guidelines that are not legally binding.

Handling and Storage

Phthalic anhydride should be stored in a cool, dry, well-ventilated area away from moisture and incompatible substances. Containers should be tightly closed when not in use to avoid contact with air and humidity, which can cause degradation.

FAQs

How is phthalic anhydride made?

Phthalic anhydride is made by the catalytic oxidation of o-xylene or naphthalene, which are derived from petroleum refining.

Is phthalic anhydride used in consumer products?

Phthalic anhydride itself isn’t used in consumer products. It’s mainly a building block to make other materials, like plasticizers and resins, which are stable and safe in their final form. As a result, people aren’t directly exposed to phthalic anhydride through everyday products.

Can phthalic anhydride cause allergic reactions?

Some workers exposed to high levels of phthalic anhydride dust or vapor may develop sensitivities, but these effects are rare, and exposures are controlled through workplace protections.

Is phthalic anhydride banned or restricted?

No. Phthalic anhydride is not banned, but it is regulated for safe use. Agencies set guidelines for workplace exposure, handling, and environmental releases.

How is phthalic anhydride transported?

Phthalic anhydride is transported either as solid flakes or as a molten liquid in sealed, labeled containers specifically designed for chemical transport.

Back to Top

For more chemical safety facts, follow us on social media.

© 2005 – 2023 American Chemistry Council, Inc. The ACC mark, Responsible Care®, the hands logo mark, CHEMTREC®, TRANSCAER®, and americanchemistry.com are registered service marks of the American Chemistry Council, Inc.